Alleviation of Podophyllotoxin Toxicity Using Coexisting Flavonoids from Dysosma versipellis
نویسندگان
چکیده
منابع مشابه
Alleviation of Podophyllotoxin Toxicity Using Coexisting Flavonoids from Dysosma versipellis
Podophyllotoxin (POD) is a lignan-type toxin existing in many herbs used in folk medicine. Until now, no effective strategy is available for the management of POD intoxication. This study aims to determine the protective effects of flavonoids (quercetin and kaempferol) on POD-induced toxicity. In Vero cells, both flavonoids protected POD-induced cytotoxicity by recovering alleviating G2/M arrest,...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0072099